Posts Tagged ‘bipolar disorder’

Joshua Walters: On being just crazy enough

A spectrum approach in mental illness is very appealing and could possibly explain why some disorders are still in the gene pool. Of course, it’s all speculative at this point but very interesting. I will try to write a bit more about this in a future blog post. For now, here is a relevant TED talk by Joshua Walters, a comedian diagnosed with bipolar disorder.

Maybe no one’s really crazy. Everyone is just a little bit mad. How much depends on where you fall in the spectrum. How much depends on how lucky you are.” (Joshua Walters)




Music and the Brain: Depression and Creativity Symposium

22/01/2012 8 comments

If you’re following this blog, you probably know that I’m very interested in creativity. I was delighted to find this video on YouTube and decided to share it with you:

Kay Redfield Jamison, professor of psychiatry and behavioral sciences and co-director of the Johns Hopkins Mood Disorders Center at the Johns Hopkins University School of Medicine, convened a discussion of the effects of depression on creativity. Joining Jamison were two distinguished colleagues from the fields of neurology and neuropsychiatry, Dr. Terence Ketter and Dr. Peter Whybrow. The Music and the Brain series is co-sponsored by the Library’s Music Division and Science, Technology and Business Division, in cooperation with the Dana Foundation.

The “Depression and Creativity” symposium marks the bicentennial of the birth of German composer Felix Mendelssohn (1809-1847), who died after a severe depression following the death of his sister, Fanny Mendelssohn Hensel, also a gifted composer.

One of the nation’s most influential writers on creativity and the mind, Kay Redfield Jamison is a noted authority on bipolar disorder. She is the co-author of the standard medical text on manic-depressive illness and author of “Touched with Fire,” “An Unquiet Mind,” “Night Falls Fast” and “Exuberance: The Vital Emotion.”

Dr. Terence Ketter is known for extensive clinical work with exceptionally creative individuals and a strong interest in the relationship of creativity and madness. He is professor of psychiatry and behavioral sciences and chief of the Bipolar Disorders Clinic at Stanford University School of Medicine.

Dr. Peter Whybrow, an authority on depression and manic-depressive disease, is director of the Semel Institute for Neuroscience and Human Behavior at the University of California, Los Angeles (UCLA). He is also the Judson Braun Distinguished Professor and executive chair of the Department of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine at UCLA. (description take from here).

And here’s the video:

Mental Illness and Creativity

23/07/2009 10 comments

ArtisticRavenThe idea that creativity is strongly associated with mental illness was popular since Aristotle’s era. Many recent studies seem to support this claim.

Here are a few findings that suggest that the link between art and mental illness really exists:

  1. 1. Researchers (Jamison, 1989; Janka, 2004) have found high levels of psychopathology, especially, depression and bipolar disorder (I, II & cyclothymia) in writers, poets, visual artists and composers, compared to the rates in the general population. Furthermore, artistic creatives and psychiatric patients share a tendency to unusual ideas and experiences. Moreover, different domains of creativity require different cognitive profiles, with poetry and art associated with divergent thinking, schizophrenia and affective disorder (Nettle, 2005).
  2. Family studies have produced evidence of creative interests and aptitudes in close relatives of psychiatric patients, including biological relatives separated by adoption (Andreasen, 1987). This supports the idea that there is an inherited personality or cognitive trait that has both creativity and mental illness in its range of effects.
  3. Research on psychiatric patients, usually with a diagnosis of schizophrenia, suggest that they have enhanced performance relative to control participants on tasks  that require divergent thinking  (Hasenfus & Magaro, 1976; Jamison, 1989). Divergent thinking is strongly connected to creativity.
  4. A new theory based on genetics suggest that gene mutations that increase a person’s risk of developing mental illnesses such as schizophrenia and bipolar syndrome have been preserved, even preferred, during human evolution, due to their relationship with creativity. More specifically, a specific gene, neuregulin 1 is linked to a slightly increased risk of schizophrenia. Mutations to this gene were found to be linked with psychosis, poor memory and sensitive to criticism. About 50 per cent of healthy Europeans have one copy of this mutation, while 15 per cent possess two copies. People with two copies of the neuregulin 1 mutation tended to score notably higher on these measures of creativity, compared with other volunteers with one or no copy of the mutation. A significant increase in creativity relative to participants with no copy of this gene was found to people possessing only one copy of the mutation. However, the mutation of neuregulin 1 can explain only a small part of the differences in creativity levels (Kéri, 2009). Other researchers  (Nettle & Clegg, 2005) “blame” the artists for the persistence of schizophrenia, as they have schizotypal personality traits and are more successful in finding sexual partners compared to non artistic individuals. However, this idea isn’t that popular among artists.
  5. Symptoms of certain disorders like hypomania (mild mania) favour creativity by giving a boost to the imagination and energy. On the other hand, full blown symptoms or more serious disorders have the opposite effect and inhibit creativity.

Suggested readings:
Artistic tendencies linked to ‘schizophrenia gene – New Scientist article

A beautiful mind – BBC News

Manic-Depressive Illness and Creativity by K.R. Jamison – Scientific American

Creativity andmental health by J. Schlesinger – The British Journal of Psychiatry

Connecting Depression and Artistry by R.A. Friedman (MD) – The New York Times

Biological Basis For Creativity Linked To Mental Illness – Science Daily

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